Market Size & Trends

The global hormone replacement therapy market size was valued at USD 21.28 billion in 2022 and is expected to grow at a compounded annual growth rate (CAGR) of 6.6% from 2023 to 2030. The hormone replacement therapy (HRT) market is witnessing growth due to factors such as the rising incidence of target diseases and the availability of long-acting hGH products. According to American Thyroid Association, around 12.0% of the U.S. population is estimated to suffer from thyroid during their lifetime. It also reported that approximately 20.0 million U.S. citizens have some form of thyroid disease. Several studies showed that people who are on hormone replacement therapy are likely to have a low risk of COVID-19 infection and mortality rate.

A study led by the Oxford-Royal College of General Practitioners Research and Surveillance Centre studied 1.8 million medical records of women from 465 general practitioners and found 5,451 COVID cases linked with HRT (estrogen therapy treatment) witnessed a 78% reduction in infection and mortality rate. The male population tends to have a more severe infection and higher rates of hospitalization and mortality.

Gather more insights about the market drivers, restrains and growth of the Global Hormone Replacement Therapy Market

Product Insights

Based on product, the HRT market is segmented into estrogen & progesterone replacement therapy, hGH replacement therapy, thyroid replacement therapy, parathyroid hormone replacement, and testosterone replacement therapy. The estrogen and progesterone replacement therapy segment held the highest market share of 54.34% in 2022. The dominance was attributed due to an increase in the number of women suffering from menopause. According to the American Congress of Obstetricians and Gynecologists, around 6,000 women reach menopause daily in the U.S.

Route Of Administration Insights

Based on route of administration, HRT market is segmented into oral, parenteral, transdermal, and others. The oral segment dominated the market with a share of 42.48% in 2022 due to high prescription rate and ease of administration. Most HRT products generally include pills & tablets.

Disease Type Insights

Based on disease type, HRT market has been segmented into menopause, male hypogonadism, hypothyroidism, growth hormone deficiency, and hypoparathyroidism. The menopause segment dominated the market in 2022 with a share of 44.44%. This can be attributed to the owing to increase in the number of women suffering from menopause.

Regional Insights

North America dominated the global hormone replacement therapy market with a share of 39.15% in 2022 and is anticipated to grow at a significant rate over the forecast period. Major product launches, collaborative agreements between manufacturers, and favorable reimbursement policies are among factors responsible for the largest market share in the region.

Key Companies & Market Share Insights

Key companies are undertaking strategic initiatives to address the growing demand for hormone replacement therapy products. In November 2021, I-MAB Biopharma Co., Ltd. entered into a collaboration with Jumpcan Pharmaceutical Group for the development & commercialization of eftansomatropin alfa (TJ101) in China. TJ101 is a long-acting recombinant human growth hormone, which is currently under phase 3 clinical trial for the treatment of pediatric growth hormone deficiency. This collaboration is expected to strengthen its position in the hormone replacement therapy market. Additionally, in February 2023, Korea’s Ministry of Food and Drug Safety approved Pfizer’s NGENLA for the treatment of growth hormone deficiency.

Some of the key players in the global hormone replacement therapy market include:

• Eli Lilly and Company
• Bayer AG
• Noven Pharmaceuticals, Inc.
• Pfizer Inc.
• Merck & Co., Inc.
• Viatris, Inc.
• Novo Nordisk A/S
• F. Hoffmann-La Roche Ltd.
• ASCEND Therapeutics US, LLC.
• AbbVie, Inc.

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Hormone Replacement Therapy Market Segmentation

Grand View Research has segmented the hormone replacement therapy market by product, route of administration, disease type, and region:

Hormone Replacement Therapy Product Outlook (Revenue, USD Billion, 2018 - 2030)

• Estrogen & Progesterone Replacement Therapy
• HGH replacement therapy
• Thyroid hormone replacement therapy
• Testosterone Replacement Therapy
• Parathyroid Hormone Replacement

Hormone Replacement Therapy Route of Administration Outlook (Revenue, USD Billion, 2018 - 2030)

• Oral
• Parenteral
• Transdermal
• Others

Hormone Replacement Therapy Disease Type Outlook (Revenue, USD Billion, 2018 - 2030)

• Menopause
• Hypothyroidism
• Male hypogonadism
• Growth hormone deficiency
• Hypoparathyroidism

Hormone Replacement Therapy Regional Outlook (Revenue, USD Billion, 2018 - 2030)

• North America
• U.S.
• Canada
• Europe
• Germany
• UK
• France
• Italy
• Spain
• Denmark
• Sweden
• Norway
• Asia Pacific
• Japan
• China
• India
• Australia
• South Korea
• Thailand
• Latin America
• Brazil
• Mexico
• Argentina
• Middle East and Africa (MEA)
• South Africa
• Saudi Arabia
• UAE
• Kuwait

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